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1

Clay nanoparticles for regenerative medicine and biomaterial design: a review of clay bioactivity

Mousa, Mohamed, Evans, Nicholas D., Oreffo, Richard O.C., Dawson, Jonathan I.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.40 MB

english, 2018

2

Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate

Dalby, Matthew J., Gadegaard, Nikolaj, Oreffo, Richard O. C.

Journal:

Nature Materials

Year:

2014

Language:

english

File:

PDF, 3.19 MB

english, 2014

3

The chorioallantoic membrane (CAM) assay for the study of human bone regeneration: a refinement animal model for tissue engineering

Moreno-Jiménez, Inés, Hulsart-Billstrom, Gry, Lanham, Stuart A., Janeczek, Agnieszka A., Kontouli, Nasia, Kanczler, Janos M., Evans, Nicholas D., Oreffo, Richard OC

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.28 MB

english, 2016

4

Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes

Alvarez, Karl, de Andrés, María C, Takahashi, Atsushi, Oreffo, Richard O C

Journal:

BMC Musculoskeletal Disorders

Year:

2014

Language:

english

File:

PDF, 501 KB

english, 2014

5

Preservation and stability of cell therapy products: recommendations from an expert workshop

Stacey, Glyn N, Connon, Che J, Coopman, Karen, Dickson, Alan J, Fuller, Barry, Hunt, Charles J, Kemp, Paul, Kerby, Julie, Man, Jennifer, Matejtschuk, Paul, Moore, Harry, Morris, John, Oreffo, Richard

Journal:

Regenerative Medicine

Year:

2017

Language:

english

File:

PDF, 992 KB

english, 2017

6

Translation of remote control regenerative technologies for bone repair

Markides, Hareklea, McLaren, Jane S., Telling, Neil D., Alom, Noura, Al-Mutheffer, E’atelaf A., Oreffo, Richard O. C., Zannettino, Andrew, Scammell, Brigitte E., White, Lisa J., El Haj, Alicia J.

Journal:

npj Regenerative Medicine

Year:

2018

Language:

english

File:

PDF, 3.39 MB

english, 2018

7

Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model

Vishnubalaji, Radhakrishnan, Atteya, Muhammad, Al-Nbaheen, May, Oreffo, Richard O. C., Aldahmash, Abdullah, Alajez, Nehad M.

Journal:

Stem Cells International

Year:

2015

Language:

english

File:

PDF, 17.39 MB

english, 2015

8

A blueprint for translational regenerative medicine

Armstrong, James P. K., Keane, Timothy J., Roques, Anne C., Patrick, P. Stephen, Mooney, Claire M., Kuan, Wei-Li, Pisupati, Venkat, Oreffo, Richard O. C., Stuckey, Daniel J., Watt, Fiona M., Forbes, S

Journal:

Science Translational Medicine

Year:

2020

File:

PDF, 385 KB

2020

9

Combinatorial Delivery of Bioactive Molecules by a Nanoparticle-Decorated and Functionalized Biodegradable Scaffold

Czekanska, Ewa, Geng, Jin, Glinka, Michael, White, Kate, Kanczler, Janos M., Evans, Nicholas D, Oreffo, Richard O, Bradley, Mark

Journal:

Journal of Materials Chemistry B

Year:

2018

Language:

english

File:

PDF, 1.30 MB

english, 2018

10

Hope versus hype: what can additive manufacturing realistically offer trauma and orthopedic surgery?

Gibbs, David MR, Vaezi, Mohammad, Yang, Shoufeng, Oreffo, Richard OC

Journal:

Regenerative Medicine

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

11

Trapping single human osteoblast-like cells from a heterogeneous population using a dielectrophoretic microfluidic device

Thomas, Rupert S. W., Mitchell, Peter D., Oreffo, Richard O. C., Morgan, Hywel

Journal:

Biomicrofluidics

Year:

2010

Language:

english

File:

PDF, 906 KB

english, 2010

12

Cell Engineering and Regeneration || Cell Culture Conditions: Cultivation of Stem Cells Under Dynamic Conditions

Gimble, Jeffrey M., Marolt, Darja, Oreffo, Richard, Redl, Heinz, Wolbank, Susanne

Year:

2018

Language:

english

File:

PDF, 609 KB

english, 2018

13

Human bone marrow osteoprogenitors express estrogen receptor-alpha and bone morphogenetic proteins 2 and 4 mRNA during osteoblastic differentiation

Richard O.C. Oreffo, Vesna Kusec, Silke Romberg, James T. Triffitt

Journal:

Journal of Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 258 KB

english, 1999

14

Pleiotrophin/Osteoblast-Stimulating Factor 1: Dissecting Its Diverse Functions in Bone Formation

Rahul S. Tare, Richard O. C. Oreffo, Nicholas M. P. Clarke, Helmtrud I. Roach

Journal:

Journal of Bone and Mineral Research

Year:

2002

Language:

english

File:

PDF, 20.31 MB

english, 2002

15

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency

McMurray, Rebecca J., Gadegaard, Nikolaj, Tsimbouri, P. Monica, Burgess, Karl V., McNamara, Laura E., Tare, Rahul, Murawski, Kate, Kingham, Emmajayne, Oreffo, Richard O. C., Dalby, Matthew J.

Journal:

Nature Materials

Year:

2011

Language:

english

File:

PDF, 1.25 MB

english, 2011

16

Bcl-2-associated athanogene-1 (BAG-1): A transcriptional regulator mediating chondrocyte survival and differentiation during endochondral ossification

Rahul S. Tare, Paul A. Townsend, Graham K. Packham, Stefanie Inglis, Richard O.C. Oreffo

Journal:

Year:

2008

Language:

english

File:

PDF, 2.90 MB

english, 2008

17

Stimulation of human bone marrow stromal cells using growth factor encapsulated calcium carbonate porous microspheres

Green, David, Walsh, Dominic, Yang, Xeubin, Mann, Stephen, Oreffo, Richard O. C.

Journal:

Journal of Materials Chemistry

Year:

2004

Language:

english

File:

PDF, 719 KB

english, 2004

18

Epigenetic Aspects of Chronic Diseases || Epigenetics and Type 2 Diabetes

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 1.71 MB

english, 2011

19

Taking tissue engineering principles into theatre: retrieval analysis from a clinically translated case

Aarvold, Alexander, Smith, James O, Tayton, Edward R, Tilley, Simon, Dawson, Jon I, Lanham, Stuart A, Briscoe, Adam, Dunlop, Douglas G, Oreffo, Richard OC

Journal:

Regenerative Medicine

Year:

2011

Language:

english

File:

PDF, 4.06 MB

english, 2011

20

Regionally-derived cell populations and skeletal stem cells from human foetal femora exhibit specific osteochondral and multi-lineage differentiation capacityin vitroandex vivo

Gothard, David, Cheung, Kelvin, Kanczler, Janos M., Wilson, David I., Oreffo, Richard O. C.

Journal:

Stem Cell Research & Therapy

Year:

2015

Language:

english

File:

PDF, 4.52 MB

english, 2015

21

The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases

Budd, Emma, Waddell, Shona, de Andrés, María C., Oreffo, Richard O. C.

Journal:

Current Molecular Biology Reports

Year:

2017

Language:

english

File:

PDF, 700 KB

english, 2017

22

Epigenetic Regulation during Fetal Femur Development: DNA Methylation Matters

de Andrés, María C., Kingham, Emmajayne, Imagawa, Kei, Gonzalez, Antonio, Roach, Helmtrud I., Wilson, David I., Oreffo, Richard O. C., Neves, Nuno M.

Journal:

Year:

2013

Language:

english

File:

PDF, 995 KB

english, 2013

23

Cell Engineering and Regeneration || Embryonic Stem Cells

Gimble, Jeffrey M., Marolt, Darja, Oreffo, Richard, Redl, Heinz, Wolbank, Susanne

Year:

2017

Language:

english

File:

PDF, 970 KB

english, 2017

24

Cell Engineering and Regeneration || Cell Sheets for Tissue Engineering Applications

Gimble, Jeffrey M., Marolt, Darja, Oreffo, Richard, Redl, Heinz, Wolbank, Susanne

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

25

Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

Kim, Yang-Hee, Yang, Xia, Shi, Liyang, Lanham, Stuart A., Hilborn, Jons, Oreffo, Richard O. C., Ossipov, Dmitri, Dawson, Jonathan I.

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 2.87 MB

english, 2020

26

Development of a slow non-viral DNA release system from PDLLA scaffolds fabricated using a supercritical CO2 technique

Mieke Heyde, Kris A. Partridge, Steven M. Howdle, Richard O.C. Oreffo, Martin C. Garnett, Kevin M. Shakesheff

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 530 KB

english, 2007

27

Growth and differentiation of human bone marrow osteoprogenitors on novel calcium phosphate cements

Richard O.C. Oreffo, Ferdinand C.M. Driessens, Josep A. Planell, James T. Triffitt

Journal:

Year:

1998

Language:

english

File:

PDF, 876 KB

english, 1998

28

In search of the skeletal stem cell: isolation and separation strategies at the macro/micro scale for skeletal regeneration

Gothard, David, Tare, Rahul S., Mitchell, Peter D., Dawson, Jonathan I., Oreffo, Richard O. C.

Journal:

Year:

2011

Language:

english

File:

PDF, 573 KB

english, 2011

29

Taking tissue-engineering principles into theater: augmentation of impacted allograft with human bone marrow stromal cells

Tilley, Simon, Bolland, Benjamin JRF, Partridge, Kris, New, Andrew MR, Latham, Jeremy M, Dunlop, Douglas G, Oreffo, Richard OC

Journal:

Regenerative Medicine

Year:

2006

Language:

english

File:

PDF, 301 KB

english, 2006

30

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes

de Andrés, María C., Imagawa, Kei, Hashimoto, Ko, Gonzalez, Antonio, Roach, Helmtrud I., Goldring, Mary B., Oreffo, Richard O. C.

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

31

Nanotopographical Effects on Mesenchymal Stem Cell Morphology and Phenotype

Tsimbouri, Penelope, Gadegaard, Nikolaj, Burgess, Karl, White, Kate, Reynolds, Paul, Herzyk, Pawel, Oreffo, Richard, Dalby, Matthew J.

Journal:

Journal of Cellular Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.67 MB

english, 2014

32

Patients with Primary Osteoarthritis Show No Change with Ageing in the Number of Osteogenic Precursors

Richard Oreffo, Andrea Bennett, And,

Journal:

Scandinavian Journal of Rheumatology

Year:

1998

Language:

english

File:

PDF, 248 KB

english, 1998

33

Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells

Terje Sjöström, Matthew J. Dalby, Andrew Hart, Rahul Tare, Richard O.C. Oreffo, Bo Su

Journal:

Acta Biomaterialia

Year:

2009

Language:

english

File:

PDF, 4.26 MB

english, 2009

34

A microarray approach to the identification of polyurethanes for the isolation of human skeletal progenitor cells and augmentation of skeletal cell growth

Rahul S. Tare, Ferdous Khan, Guilhem Tourniaire, Suzanne M. Morgan, Mark Bradley, Richard O.C. Oreffo

Journal:

Year:

2009

Language:

english

File:

PDF, 822 KB

english, 2009

35

Clay: New Opportunities for Tissue Regeneration and Biomaterial Design

Dawson, Jonathan I., Oreffo, Richard O. C.

Journal:

Advanced Materials

Year:

2013

Language:

english

File:

PDF, 5.28 MB

english, 2013

36

Adult mesenchymal stem cells and impaction grafting: a new clinical paradigm shift

Bolland, Benjamin JRF, Tilley, Simon, New, Andrew MR, Dunlop, Douglas G, Oreffo, Richard OC

Journal:

Expert Review of Medical Devices

Year:

2007

Language:

english

File:

PDF, 680 KB

english, 2007

37

Acoustically modulated biomechanical stimulation for human cartilage tissue engineering

Jonnalagadda, Umesh S., Hill, Martyn, Messaoudi, Walid, Cook, Richard B., Oreffo, Richard O. C., Glynne-Jones, Peter, Tare, Rahul S.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.63 MB

english, 2018

38

Characterization of New PEEK/HA Composites with 3D HA Network Fabricated by Extrusion Freeforming

Vaezi, Mohammad, Black, Cameron, Gibbs, David, Oreffo, Richard, Brady, Mark, Moshrefi-Torbati, Mohamed, Yang, Shoufeng

Journal:

Year:

2016

Language:

english

File:

PDF, 7.72 MB

english, 2016

39

Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature

Spitzhorn, Lucas-Sebastian, Megges, Matthias, Wruck, Wasco, Rahman, Md Shaifur, Otte, Jörg, Degistirici, Özer, Meisel, Roland, Sorg, Rüdiger Volker, Oreffo, Richard O. C., Adjaye, James

Journal:

Stem Cell Research & Therapy

Year:

2019

File:

PDF, 8.90 MB

2019

40

The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation

Janos M. Kanczler, Patrick J. Ginty, Lisa White, Nicholas M.P. Clarke, Steven M. Howdle, Kevin M. Shakesheff, Richard O.C. Oreffo

Journal:

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

41

Changes in the antiangiogenic properties of articular cartilage in osteoarthritis

James O. Smith, Richard O.C. Oreffo, Nicholas M.P. Clarke, Helmtrud I. Roach

Journal:

Journal of Orthopaedic Science

Year:

2003

Language:

english

File:

PDF, 364 KB

english, 2003

42

Surface mobility regulates skeletal stem cell differentiation

González-García, Cristina, Moratal, David, Oreffo, Richard O. C., Dalby, Matthew J., Salmerón-Sánchez, Manuel

Journal:

Integrative Biology

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

43

Tracking adipogenic differentiation of skeletal stem cells by label-free chemically selective imaging

Smus, Justyna P., Moura, Catarina Costa, McMorrow, Emma, Tare, Rahul S., Oreffo, Richard O. C., Mahajan, Sumeet

Journal:

Chemical Science

Year:

2015

Language:

english

File:

PDF, 829 KB

english, 2015

44

The application of human bone marrow stromal cells and poly(dl-lactic acid) as a biological bone graft extender in impaction bone grafting

Benjamin J.R.F. Bolland, Janos M. Kanczler, Patrick J. Ginty, Steve M. Howdle, Kevin M. Shakesheff, Douglas G. Dunlop, Richard O.C. Oreffo

Journal:

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

45

Formation of a human-derived fat tissue layer in PdlLGA hollow fibre scaffolds for adipocyte tissue engineering

Suzanne M. Morgan, Ben J. Ainsworth, Janos M. Kanczler, Jodie C. Babister, Julian B. Chaudhuri, Richard O.C. Oreffo

Journal:

Year:

2009

Language:

english

File:

PDF, 2.76 MB

english, 2009

46

Activation of the bone-derived latent TGF beta complex by isolated osteoclasts

Richard O.C. Oreffo, Gregory R. Mundy, Saeid M. Seyedin, Lynda F. Bonewald

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 470 KB

english, 1989

47

Tissue engineering strategies for cartilage generation—Micromass and three dimensional cultures using human chondrocytes and a continuous cell line

Rahul S. Tare, Daniel Howard, Jodie C. Pound, Helmtrud I. Roach, Richard O.C. Oreffo

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 4.21 MB

english, 2005

48

Embryonic and Induced Pluripotent Stem Cells: Understanding, Creating, and Exploiting the Nano-Niche for Regenerative Medicine

Kingham, Emmajayne, Oreffo, Richard O.C.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

49

Developmental Cues for Bone Formation from Parathyroid Hormone and Parathyroid Hormone-Related Protein in an Ex Vivo Organotypic Culture System of Embryonic Chick Femora

Smith, Emma L., Kanczler, Janos M., Roberts, Carol A., Oreffo, Richard O.C.

Journal:

Tissue Engineering Part C Methods

Year:

2012

Language:

english

File:

PDF, 1.69 MB

english, 2012

50

MicroRNA-146a Regulates Human Foetal Femur Derived Skeletal Stem Cell Differentiation by Down-Regulating SMAD2 and SMAD3

Cheung, Kelvin S. C., Sposito, Nunzia, Stumpf, Patrick S., Wilson, David I., Sanchez-Elsner, Tilman, Oreffo, Richard O. C., Alajez, Nehad M.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.13 MB

english, 2014

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